Viperin Turns Coat in Cytomegalovirus Infection

Publication year: 2011
Source: Developmental Cell, Volume 20, Issue 6, 14 June 2011, Pages 737-738

Lorenzo, Galluzzi , Oliver, Kepp , Guido, Kroemer

Cytomegalovirus infection is associated with cytoskeletal alterations and cell swelling (cytomegaly), which have been attributed to the viral mitochondria-localized inhibitor of apoptosis (vMIA) protein. In a recent issue of Science, Seo et al. (2011) showed that the antiviral host protein viperin is co-opted to function with vMIA for facilitating infection.