Vaccine production, distribution, access, and uptake

Publication year: 2011
Source: The Lancet, In Press, Corrected Proof, Available online 12 June 2011

Jon, Smith , Marc, Lipsitch , Jeffrey W, Almond

For human vaccines to be available on a global scale, complex production methods, meticulous quality control, and reliable distribution channels are needed to ensure that the products are potent and effective at the point of use. The technologies used to manufacture different types of vaccines can strongly affect vaccine cost, ease of industrial scale-up, stability, and, ultimately, worldwide availability. The complexity of manufacturing is compounded by the need for different formulations in different countries and age-groups. Reliable vaccine production in appropriate quantities and at affordable prices is the cornerstone of developing global vaccination policies. However, to ensure optimum access and…