Triglyceride–high-density lipoprotein cholesterol is associated with microvascular complications in type 2 diabetes mellitus

Publication year: 2011
Source: Metabolism, In Press, Corrected Proof, Available online 14 June 2011

Giacomo, Zoppini , Carlo, Negri , Vincenzo, Stoico , Stefano, Casati , Isabella, Pichiri , …

The purpose of this study was to evaluate whether a high triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratio is associated with an increased incidence of retinopathy and chronic kidney disease (CKD) in type 2 diabetes mellitus. Individuals with type 2 diabetes mellitus (n = 979) with an estimated glomerular filtration rate greater than 60 mL/min and without retinopathy and cardiovascular disease at baseline were followed up for the incidence of diabetic retinopathy (diagnosed by retinography) and CKD (diagnosed by estimated glomerular filtration rate ≤60 mL/min/1.73 m2). On follow-up (mean, 4.9 years), 217 (22.2% of total) subjects experienced CKD and/or diabetic-specific retinal lesions…