The effects of dietary nickel on the detoxification enzymes, innate immunity and resistance to the fungus Beauveria bassiana in the larvae of the greater wax moth Galleria mellonella

Publication year: 2011
Source: Chemosphere, In Press, Corrected Proof, Available online 14 June 2011

I.M., Dubovskiy , E.V., Grizanova , N.S., Ershova , M.J., Rantala , V.V., Glupov

In this study, we tested the effects of dietary nickel on the activity of glutathione S-transferase (GST), esterases, phenoloxidase, and encapsulation in the haemolymph of larvae of the greater wax moth Galleria mellonella. We also explored the effects of dietary nickel on larval resistance to infection by the fungus Beauveria bassiana. Larvae fed a low dose of nickel (10μgg−1) had significantly higher GST, phenoloxidase activity and encapsulation responses than controls fed on a nickel-free diet. We also found that larvae fed a sublethal dose of nickel (50μgg−1) had increased GST, esterase activity and encapsulation rates but decreased phenoloxidase activity. Although,…

 Highlights: ► Low dose of Ni increases detoxification enzymes activity and immunity reactions. ► There is no effect of the low dose of Ni on the resistance of the insects against the fungus. ► Sublethal Ni increases GST, esterases activity and encapsulation rate but decreases PO activity. ► Sublethal Ni enhances immunity but the resistance against the real pathogen reduced.