Quality of Life in a German Graves Orbitopathy Population

Publication year: 2011
Source: American Journal of Ophthalmology, In Press, Corrected Proof, Available online 14 June 2011

Katharina A., Ponto , Gerhard, Hommel , Susanne, Pitz , Heike, Elflein , Norbert, Pfeiffer , …

 Purpose: To evaluate the validity and responsiveness of a German-language version of the disease-specific Graves orbitopathy quality-of-life questionnaire (GO-QOL). Design: Prospective cross-sectional study. Methods: At a multidisciplinary university orbital center, 310 consecutive unselected Graves orbitopathy outpatients answered the GO-QOL before undergoing complete ophthalmic and endocrine assessment. The main outcome measures were the GO-QOL and its 2 subscales, Visual Functioning and Appearance. Results: The QOL scores for the subscales Visual Functioning and Appearance were (mean ± SE) 72.5 ± 1.4 and 71.3 ± 1.5, respectively. Visual Functioning and Appearance were higher in mild (82.2 ± 2.2 and 86.0 ± 17.6) than in moderate to severe (66.6 ± 1.8,…