Histochemical and ultrastructural changes of sternomastoid muscle in aged wistar rats

Publication year: 2011
Source: Micron, In Press, Accepted Manuscript, Available online 13 June 2011

Adriano Polican, Ciena , Sonia Regina Yokomizo de, Almeida , Paulo Henrique de Matos, Alves , Regina, de Sousa Bolina-Matos , Fernando José, Dias , …

The aim of this study was to evaluate histochemically and ultrastructurally the sternomastoid muscle (SM) of adults and aged rats, employing histochemic (NADH-TR reaction) and transmission electron microscopic methods. It was used twenty rats, divided into two groups: adults (n=10), animals with 4 months of age, and aged group (n=10), animals with 24 months of age. Five animals from each group were anesthetized with an overdose of urethane (3g / kg i.p.), and the muscles dissected after the samples processing for histochemical reaction (NADH-TR). Three types of fibers were identified by their metabolic characteristics: fibers with high oxidative capacity (O),…