Effects of oxcarbazepine treatment on serum lipids and carotid intima media thickness in children

Publication year: 2011
Source: Brain and Development, In Press, Corrected Proof, Available online 14 June 2011

Uluç, Yiş , Mustafa, Doğan

The aim of this study is to evaluate the carotid intima media thickness and serum lipids in pediatric patients with epilepsy treated with oxcarbazepine. The study included 21 pediatric epileptic and 22 healthy children. Intima media thickness and fasting lipid profile were assessed. Although the median value of total cholesterol was in normal limits in the oxcarbazepine group, it was significantly higher when compared with the control group. We did not observe any differences regarding triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and carotid intima media thickness. We suggest that oxcarbazepine treatment in children has a minor effect on serum…